The study assessed Genetic High Myopia at Onset and Progression in School-aged Children with Visual Impairment in Rivers State, Nigeria. The design adopted in this study was a survey research design. One research question and one corresponding hypothesis guided the conduct of the study. The sampling technique used was the stratified sampling technique. A self-structured questionnaire was employed as an instrument for data collection. An expert in Special Needs Education and two experts in Measurement and Evaluation validated the instrument. The reliability coefficient was obtained using Cronbach’s alpha. Mean rating was used in answering the research question and independent sample t-test analysis was used to test the hypothesis at 0.05 significance level. The Statistical Package for Social Science (SPSS) aided the data analysis. The study revealed that to a high extent, parental refractive error is a risk factor of high genetic myopia at onset and progression amongst school-aged children with visual impairment in Rivers State, Nigeria. The study recommended that the heritability susceptibility theory of high myopia may not be disputed, therefore, parents should take their children for regular optical evaluation especially where one or both parents have refractive error to control the progression of myopia to elevated levels which causes visual impairment.